Title : Effects of vitamin D on insulin resistance and myosteatosis in diet-induced obese mice.

Pub. Date : 2018

PMID : 29342166






3 Functional Relationships(s)
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1 Consistently, a significantly decreased activation of the SCAP/SREBP lipogenic pathway and lower levels of CML protein adducts and RAGE expression were observed in skeletal muscle of animals treated with vitamin D. Vitamin D SREBF chaperone Mus musculus
2 Collectively, these data indicate that vitamin D-induced selective inhibition of signaling pathways (including NF-kappaB, SCAP/SREBP and CML/RAGE cascades) within the skeletal muscle significantly contributed to the beneficial effects of vitamin D supplementation against diet-induced metabolic derangements. Vitamin D SREBF chaperone Mus musculus
3 Collectively, these data indicate that vitamin D-induced selective inhibition of signaling pathways (including NF-kappaB, SCAP/SREBP and CML/RAGE cascades) within the skeletal muscle significantly contributed to the beneficial effects of vitamin D supplementation against diet-induced metabolic derangements. Vitamin D SREBF chaperone Mus musculus