Title : Activities of ectonucleotidases and adenosine deaminase in platelets of cattle experimentally infected by Fasciola hepatica.

Pub. Date : 2017 May

PMID : 28242355






3 Functional Relationships(s)
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1 The enzymatic activities of NTPDase, 5"-nucleotidase and adenosine deaminase (ADA) are important in regulating the concentration of adenine nucleotides, molecules known to be involved on platelet aggregation. Adenine Nucleotides 5'-nucleotidase Bos taurus
2 Taking into consideration the association between the purinergic system and hemostasis, this study aimed to evaluate the enzymatic activities of NTPDase (hydrolyze ATP and ADP), 5"-nucleotidase (hydrolyze AMP) and ADA (deamination of adenosine) in platelets from cattle experimentally infected by Fasciola hepatica on days 20, 40, 60 and 80 post-infection (PI). Adenosine Monophosphate 5'-nucleotidase Bos taurus
3 Reduction of NTPDase (p < 0.05) hydrolysing ATP (days 20, 40 and 60 PI), and ADP (days 40, 60 and 80 PI), and on 5"-nucleotidase hydrolyzing AMP (days 40 and 60 PI) was observed. Adenosine Monophosphate 5'-nucleotidase Bos taurus