Pub. Date : 2016 Jun
PMID : 27137487
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Fasting-induced liver GADD45beta restrains hepatic fatty acid uptake and improves metabolic health. | hepatic fatty acid | growth arrest and DNA-damage-inducible 45 beta | Mus musculus |
| 2 | Using whole-body knockout mice as well as liver/hepatocyte-specific gain- and loss-of-function strategies, we revealed a role for liver GADD45beta in the coordination of liver fatty acid uptake, through cytoplasmic retention of FABP1, ultimately impacting obesity-driven hyperglycaemia. | Fatty Acids | growth arrest and DNA-damage-inducible 45 beta | Mus musculus |