Pub. Date : 2015 Sep 5
PMID : 26054750
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 1,25-Dihydroxyvitamin D3 and extracellular calcium promote mineral deposition via NPP1 activity in a mature osteoblast cell line MLO-A5. | Calcitriol | ectonucleotide pyrophosphatase/phosphodiesterase 1 | Mus musculus |
| 2 | 1,25-Dihydroxyvitamin D3 and extracellular calcium promote mineral deposition via NPP1 activity in a mature osteoblast cell line MLO-A5. | Calcium | ectonucleotide pyrophosphatase/phosphodiesterase 1 | Mus musculus |
| 3 | Since MLO-A5 cells express abundant alkaline phosphatase that was not further modified by 1,25D treatment or exposure to increased calcium, this finding suggested that the NPP1 production of pyrophosphate (PPi) may provide alkaline phosphatase with substrate for the generation of inorganic phosphate (Pi). | diphosphoric acid | ectonucleotide pyrophosphatase/phosphodiesterase 1 | Mus musculus |
| 4 | Since MLO-A5 cells express abundant alkaline phosphatase that was not further modified by 1,25D treatment or exposure to increased calcium, this finding suggested that the NPP1 production of pyrophosphate (PPi) may provide alkaline phosphatase with substrate for the generation of inorganic phosphate (Pi). | Phosphates | ectonucleotide pyrophosphatase/phosphodiesterase 1 | Mus musculus |