Title : HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.

Pub. Date : 2014 Sep 25

PMID : 25242319






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We identified a PGC-1beta-mediated pathway by which HIF-1 inhibits the medium- and long-chain acyl-CoA dehydrogenases (MCAD and LCAD), resulting in decreased reactive oxygen species levels and enhanced proliferation. Reactive Oxygen Species PPARG coactivator 1 beta Homo sapiens