Title : Downregulation of ceramide synthase-6 during epithelial-to-mesenchymal transition reduces plasma membrane fluidity and cancer cell motility.

Pub. Date : 2015 Feb 19

PMID : 24632610






1 Functional Relationships(s)
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1 Furthermore, pharmacological and genetic approaches established that modulation of CerS6 expression/activity in cancer cells altered the level of C16-ceramide, which in turn influenced plasma membrane fluidity and cell motility. N-palmitoylsphingosine ceramide synthase 6 Homo sapiens