Title : Reactive oxygen species play a critical role in collagen-induced platelet activation via SHP-2 oxidation.

Pub. Date : 2014 Jun 1

PMID : 24093153






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 ROS-mediated oxidation of the active cysteine site in PTPs abrogates the PTP catalytic activity. Reactive Oxygen Species protein tyrosine phosphatase, receptor type, S Mus musculus
2 ROS-mediated oxidation of the active cysteine site in PTPs abrogates the PTP catalytic activity. Cysteine protein tyrosine phosphatase, receptor type, S Mus musculus
3 The aim of this study was to elucidate whether collagen-induced ROS generation leads to PTP oxidation, which promotes platelet stimulation. Reactive Oxygen Species protein tyrosine phosphatase, receptor type, S Mus musculus