Title : Structural study of the location of the phenyl tail of benzene sulfonamides and the effect on human carbonic anhydrase inhibition.

Pub. Date : 2013 Nov 1

PMID : 24012377






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 4ITP is a medium potency hCA I and II inhibitor (KIs of 54-75nM), a strong mitochondrial CA VA/VB inhibitor (KIs of 8.3-8.6nM) and a weak transmembrane CA inhibitor (KIs of 136-212nM against hCA IX and XII). 2-phenyl-N-(4-sulfamoylbenzyl)acetamide carbonic anhydrase 5A Homo sapiens