Pub. Date : 2011 Aug 27
PMID : 21791480
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | While being treated with doxycycline, 39.4 per cent of dogs showed an increase in alanine aminotransferase (ALT) activity and 36.4 per cent showed an increase in alkaline phosphatase (ALP) activity. | Doxycycline | alkaline phosphatase, biomineralization associated | Canis lupus familiaris |
| 2 | While being treated with doxycycline, 39.4 per cent of dogs showed an increase in alanine aminotransferase (ALT) activity and 36.4 per cent showed an increase in alkaline phosphatase (ALP) activity. | Doxycycline | alkaline phosphatase, biomineralization associated | Canis lupus familiaris |
| 3 | There was a dose-related risk of an increase in ALP activity (P=0.011, odds ratio [OR]=1.27, 95 per cent confidence interval [CI] 1.06 to 1.53), and older dogs treated with doxycycline were more likely to develop an increase in ALT activity (P=0.038, OR=1.23, 95 per cent CI 1.01 to 1.50) and vomiting (P=0.017, OR=1.11, 95 per cent CI 1.02 to 1.21). | Doxycycline | alkaline phosphatase, biomineralization associated | Canis lupus familiaris |