Title : Liver disease associated with canalicular transport defects: current and future therapies.

Pub. Date : 2010 Feb

PMID : 20034695






1 Functional Relationships(s)
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1 Current evidence indicates that ursodeoxycholic acid (UDCA) can be effective in selected patients with PFIC3 (ABCB4 deficiency), while rifampicin reduces pruritus in patients with PFIC1 (ATP8B1 deficiency) and PFIC2 (ABCB11 deficiency), and might abort cholestatic episodes in BRIC (mild ATP8B1 or ABCB11 deficiency). Rifampin ATPase phospholipid transporting 8B1 Homo sapiens