Title : Metabolism of diphenyl sulfoxide in perfused guinea pig liver. Involvement of aldehyde oxidase as a sulfoxide reductase.

Pub. Date : 1990 Nov-Dec

PMID : 1981531






1 Functional Relationships(s)
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1 These results indicate that the oxidative pathway catalyzed by cytochrome P-450-dependent monooxygenase is predominant in DPSO metabolism under normoxic conditions, whereas only under hypoxia does the reductive pathway become the major one if an electron donor for aldehyde oxidase exists in intact guinea pig liver. diphenyl sulfoxide cytochrome P450 3A14 Cavia porcellus