Title : Inhibition of p38 MAPK facilitates ex vivo expansion of skin epithelial progenitor cells.

Pub. Date : 2009 Oct

PMID : 19551450






1 Functional Relationships(s)
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1 The skin epithelial progenitor cells treated with 10 microM SB203580 formed clones that were uniformly smaller in size, longer in sustained proliferation, shorter in clone doubling time, higher in S-phase cells percentage, and lower in levels of differentiation markers such as K10 along with higher levels of stem-cell-associated markers such as p63, K15, and ABCG2 than those cultured in the conventional medium. SB 203580 keratin 15 Homo sapiens