Title : Altering the relative abundance of GABA A receptor subunits changes GABA- and ethanol-responses in Xenopus oocytes.

Pub. Date : 2009 Jun

PMID : 19382902






2 Functional Relationships(s)
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1 Acute ethanol treatment of oocytes injected with a 1:1:1 or 2:2:1 ratio of alpha2:beta2:gamma3 subunit mRNAs resulted in significant potentiation of GABA currents, whereas ethanol inhibited GABA currents in cells injected with a 6:2:1 ratio. Ethanol MGC75582, possible similarity to act2 S homeolog Xenopus laevis
2 Acute ethanol treatment of oocytes injected with a 1:1:1 or 2:2:1 ratio of alpha2:beta2:gamma3 subunit mRNAs resulted in significant potentiation of GABA currents, whereas ethanol inhibited GABA currents in cells injected with a 6:2:1 ratio. gamma-Aminobutyric Acid MGC75582, possible similarity to act2 S homeolog Xenopus laevis