Pub. Date : 2008 Nov 8
PMID : 18572307
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Triptolide inhibits interferon-gamma-induced programmed death-1-ligand 1 surface expression in breast cancer cells. | triptolide | CD274 molecule | Homo sapiens |
| 2 | In the present study, we demonstrated that triptolide was able to inhibit interferon-gamma-induced PD-L1 surface expression in human breast cancer cells. | triptolide | CD274 molecule | Homo sapiens |
| 3 | Therefore, by down-regulating PD-1/PD-L1 pathway, triptolide may also serve as a modulator to promote cancer cell-reactive immune responses. | triptolide | CD274 molecule | Homo sapiens |