Title : Protein kinases Fpk1p and Fpk2p are novel regulators of phospholipid asymmetry.

Pub. Date : 2008 Apr

PMID : 18199685






3 Functional Relationships(s)
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Protein Name
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1 Protein kinases Fpk1p and Fpk2p are novel regulators of phospholipid asymmetry. Phospholipids serine/threonine protein kinase FPK1 Saccharomyces cerevisiae S288C
2 Simultaneous disruption of FPK1 and its homolog FPK2 phenocopied the lem3Delta/dnf1Delta dnf2Delta mutants, exhibiting the impaired NBD-labeled phospholipid uptake, defects in the early endosome-to-TGN pathway in the absence of CDC50, and hyperpolarized bud growth after exposure of phosphatidylethanolamine at the bud tip. Phospholipids serine/threonine protein kinase FPK1 Saccharomyces cerevisiae S288C
3 Simultaneous disruption of FPK1 and its homolog FPK2 phenocopied the lem3Delta/dnf1Delta dnf2Delta mutants, exhibiting the impaired NBD-labeled phospholipid uptake, defects in the early endosome-to-TGN pathway in the absence of CDC50, and hyperpolarized bud growth after exposure of phosphatidylethanolamine at the bud tip. phosphatidylethanolamine serine/threonine protein kinase FPK1 Saccharomyces cerevisiae S288C