Pub. Date : 2001 Jan
PMID : 11233292
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To investigate the involvement of catecholamines and/or the cyclic AMP (cAMP) systems in the development of drug dependence, we examined whether morphine dependence was developed in tyrosine hydroxylase (TH) heterozygous (TH+/-) and cAMP response element binding protein (CREB) binding protein (CBP) heterozygous (CBP+/-) mice. | Morphine | tyrosine hydroxylase | Mus musculus |
| 2 | However, increased numbers of jumping and forepaw tremor in the TH+/- and CBP+/- mice and increased level of cAMP in the thalamus/hypothalamus of TH+/- mice were not observed. | Cyclic AMP | tyrosine hydroxylase | Mus musculus |