Title : Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein Shc.

Pub. Date : 1998 Aug

PMID : 9710204






1 Functional Relationships(s)
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1 Recent studies have suggested that tyrosine phosphorylation of Shc may play a key role in T lymphocyte proliferation via interaction of phosphorylated Shc with downstream molecules involved in activation of Ras and Myc proteins. Tyrosine MYC proto-oncogene, bHLH transcription factor Homo sapiens