Title : Influence of low molecular weight heparin and low molecular weight dextran sulfate on the inhibition of coagulation factor XIa by serpins.

Pub. Date : 1998 Jul

PMID : 9684790






3 Functional Relationships(s)
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Protein Name
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1 The second order rate constant of the inactivation of FXIa by antithrombin was increased up to 6-fold by LMWH, whereas LMWdxs had no effect. Heparin, Low-Molecular-Weight serpin family C member 1 Homo sapiens
2 LMWH at maximal therapeutic plasma levels enhanced the contribution of antithrombin to the inactivation of FXIa in plasma up to 5-fold. Heparin, Low-Molecular-Weight serpin family C member 1 Homo sapiens
3 Furthermore, LMWH but not LMWdxs slightly enhanced FXIa inhibition by antithrombin. Heparin, Low-Molecular-Weight serpin family C member 1 Homo sapiens