Pub. Date : 1998 Apr
PMID : 9536026
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells: a property of protein kinase C-mediated mood stabilizers. | Valproic Acid | myristoylated alanine rich protein kinase C substrate | Homo sapiens |
| 2 | Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells: a property of protein kinase C-mediated mood stabilizers. | Valproic Acid | myristoylated alanine rich protein kinase C substrate | Homo sapiens |
| 3 | Our current results demonstrated that valproate induces a concentration- and time-dependent reduction of MARCKS in immortalized hippocampal cells that appears to be independent of both the level of muscarinic receptor-activated PI signaling as well as the concentration of myo-inositol. | Valproic Acid | myristoylated alanine rich protein kinase C substrate | Homo sapiens |
| 4 | Furthermore, the effect on MARCKS protein is additive in the presence of therapeutic concentrations of both lithium and valproate, consistent with clinical observations regarding the enhanced efficacy of the combination treatment. | Valproic Acid | myristoylated alanine rich protein kinase C substrate | Homo sapiens |