Title : In vitro effects of prostaglandin E2 or indomethacin on the proliferation of lymphokine-activated killer cells and their cytotoxicity against bladder tumor cells in patients with bladder cancer.

Pub. Date : 1997 Nov

PMID : 9491207






3 Functional Relationships(s)
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1 In vitro effects of prostaglandin E2 or indomethacin on the proliferation of lymphokine-activated killer cells and their cytotoxicity against bladder tumor cells in patients with bladder cancer. Dinoprostone interleukin 2 Homo sapiens
2 RESULTS: The proliferation of LAK cells induced by IL-2 was inhibited by PGE2 (0.05 to 5 ng/mL) in concentration-dependent manner. Dinoprostone interleukin 2 Homo sapiens
3 CONCLUSIONS: These studies indicate that LAK cell proliferation induced by IL-2 in patients with bladder cancer is inhibited by PGE2 produced by PBMC and bladder cancer cells. Dinoprostone interleukin 2 Homo sapiens