Title : Prostaglandin E2 primes naive T cells for the production of anti-inflammatory cytokines.

Pub. Date : 1997 Dec

PMID : 9464843






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 PGE2 primes naive T cells in a dose-dependent fashion for production of high levels of IL-4, IL-10 and IL-13, and very low levels of IL-2, interferon (IFN)-gamma, tumor necrosis factor (TNF)-alpha, and TNF-beta. Dinoprostone interleukin 2 Homo sapiens
2 PGE2 does not significantly increase IL-4 production in priming cultures, whereas it suppresses IL-2 and IFN-gamma. Dinoprostone interleukin 2 Homo sapiens
3 Thus PGE2 does not act by increasing IL-4 production in priming cultures, and its effects are partly IL-4 independent and largely IL-2 independent. Dinoprostone interleukin 2 Homo sapiens