Title : DL-threo-beta-benzyloxyaspartate, a potent blocker of excitatory amino acid transporters.

Pub. Date : 1998 Feb

PMID : 9463476






2 Functional Relationships(s)
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1 DL-TBOA inhibited the uptake of [14C]glutamate in COS-1 cells expressing the human excitatory amino acid transporter-1 (EAAT1) (Ki = 42 microM) with almost the same potency as DL-threo-beta-hydroxyaspartate (Ki = 58 microM). benzyloxyaspartate solute carrier family 1 member 3 Homo sapiens
2 DL-TBOA inhibited the uptake of [14C]glutamate in COS-1 cells expressing the human excitatory amino acid transporter-1 (EAAT1) (Ki = 42 microM) with almost the same potency as DL-threo-beta-hydroxyaspartate (Ki = 58 microM). benzyloxyaspartate solute carrier family 1 member 3 Homo sapiens