Title : Early induction of apoptosis in hematopoietic cell lines after exposure to flavopiridol.

Pub. Date : 1998 Jan 15

PMID : 9427698






2 Functional Relationships(s)
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Protein Name
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1 Flavopiridol (NSC 649890; Behringwerke L86-8275, Marburg, Germany), is a potent inhibitor of cyclin dependent kinases (CDKs) 1, 2, and 4. alvocidib cyclin dependent kinase 1 Homo sapiens
2 While flavopiridol caused cell cycle arrest with decline in CDK1 activity in PC3 cells, apoptosis of SUDHL4 cells occurred without evidence of cell cycle arrest. alvocidib cyclin dependent kinase 1 Homo sapiens