Pub. Date : 1997 Oct
PMID : 9410880
5 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | Dissociation of LPA-induced cytoskeletal contraction from stress fiber formation by differential localization of RhoA. | lysophosphatidic acid | ras homolog family member A | Mus musculus | ||
| 2 | We find that LPA-induced shape changes are preceded by translocation of RhoA from the cytosol to the cell periphery. | lysophosphatidic acid | ras homolog family member A | Mus musculus | ||
| 3 | We conclude that: (1) LPA-induced cytoskeletal contraction, but not stress fiber formation, requires translocation of RhoA from the cytosol to the plasma membrane; (2) translocation of RhoA occurs independently of its activation; and (3), a non-Src tyrosine kinase is involved in RhoA-stimulated contractility. | lysophosphatidic acid | ras homolog family member A | Mus musculus | ||
| 4 | We conclude that: (1) LPA-induced cytoskeletal contraction, but not stress fiber formation, requires translocation of RhoA from the cytosol to the plasma membrane; (2) translocation of RhoA occurs independently of its activation; and (3), a non-Src tyrosine kinase is involved in RhoA-stimulated contractility. | lysophosphatidic acid | ras homolog family member A | Mus musculus | ||
| 5 | We conclude that: (1) LPA-induced cytoskeletal contraction, but not stress fiber formation, requires translocation of RhoA from the cytosol to the plasma membrane; (2) translocation of RhoA occurs independently of its activation; and (3), a non-Src tyrosine kinase is involved in RhoA-stimulated contractility. | lysophosphatidic acid | ras homolog family member A | Mus musculus | ||