Pub. Date : 1997 Oct 15
PMID : 9406911
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The number of TH-expressing neurons was increased to 55% in aFGF-treated cultures co-incubated with aFGF and both (250 microM) IBMX and (10 microM) forskolin. | 1-Methyl-3-isobutylxanthine | tyrosine hydroxylase | Homo sapiens |
| 2 | Induction of TH by aFGF and IBMX/forskolin was partially blocked by inhibitors of protein kinase, such as H7, H8 and H89, as well as pretreatment with protein (cyclohexamide) or RNA synthesis (amanitin and actinomycin D) inhibitors. | 1-Methyl-3-isobutylxanthine | tyrosine hydroxylase | Homo sapiens |
| 3 | The concomitant addition of combinations of co-activator molecules (DA, TPA and IBMX/forskolin) and aFGF resulted in the additive induction of TH. | 1-Methyl-3-isobutylxanthine | tyrosine hydroxylase | Homo sapiens |