Title : Human monocytes maintained in culture acquire functional responsiveness to platelet-activating factor that is independent of increases in protein tyrosine phosphorylation.

Pub. Date : 1997 Aug

PMID : 9269528






3 Functional Relationships(s)
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1 However, by day 2 of culture, PAF induced an increase in O2- generation that was inhibited by pretreatment with the PAF receptor antagonist WEB 2086. Superoxides PCNA clamp associated factor Homo sapiens
2 However, by day 2 of culture, PAF induced an increase in O2- generation that was inhibited by pretreatment with the PAF receptor antagonist WEB 2086. Superoxides PCNA clamp associated factor Homo sapiens
3 In contrast, pretreatment with the protein kinase C inhibitor staurosporine had no effect on PAF-induced tyrosine phosphorylation, but did inhibit PAF-induced O2- generation. Superoxides PCNA clamp associated factor Homo sapiens