Title : Metyrapone pre-treated inferior petrosal sinus sampling in the differential diagnosis of ACTH-dependent Cushing's syndrome.

Pub. Date : 1997 May

PMID : 9231057






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1 Metyrapone pre-treated inferior petrosal sinus sampling in the differential diagnosis of ACTH-dependent Cushing"s syndrome. Metyrapone proopiomelanocortin Homo sapiens
2 We hypothesized that, given the unavailability of CRF in Australia, stimulation of ACTH secretion from tumorous corticotrophs with metyrapone treatment before IPSS may be useful. Metyrapone proopiomelanocortin Homo sapiens
3 CONCLUSIONS: Metyrapone pre-treated inferior petrosal sinus sampling is safe, and appears to induce high ACTH output from pituitary corticotroph adenomas. Metyrapone proopiomelanocortin Homo sapiens