Title : Interaction of protein phosphatases and ethanol on phospholipase C-mediated intracellular signal transduction processes in rat hepatocytes: role of protein kinase A.

Pub. Date : 1996 Dec

PMID : 8986230






4 Functional Relationships(s)
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1 In addition, we studied the combined effects of cpt-cAMP and EtOH/OKA on vasopressin-induced PLC activation. Ethanol arginine vasopressin Rattus norvegicus
2 Pretreatment with EtOH caused inhibition of vasopressin-induced PLC activation. Ethanol arginine vasopressin Rattus norvegicus
3 EtOH also decreased the enhancing effect of cpt-cAMP on the responses to vasopressin. Ethanol arginine vasopressin Rattus norvegicus
4 The susceptibility to enhancement by cpt-cAMP plotted as a function of the initial rate of vasopressin-induced Ca2+ mobilization in EtOH-treated cells was similar to the pattern observed in OKA-treated cells. Ethanol arginine vasopressin Rattus norvegicus