Title : Ceramide reproduces late appearance of oxidative stress during TNF-mediated cell death in L929 cells.

Pub. Date : 1996 Nov 12

PMID : 8920943






2 Functional Relationships(s)
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1 Tumor necrosis factor alpha mediated cell death in L929 cells correlates with a late increase in reduction of the superoxide scavenger 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), suggesting an increase in MTT reduction per viable cell. Superoxides tumor necrosis factor Mus musculus
2 Our results suggest a late increase in superoxide production prior to cellular destruction during TNF and ceramide mediated cell death and support the notion that ceramide can serve as a second messenger for TNF in cell death. Superoxides tumor necrosis factor Mus musculus