Title : Establishment and hormonal regulation of a conditionally transformed preosteocytic cell line from adult human bone.

Pub. Date : 1996 Nov

PMID : 8895322






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Vitamin D3 also increased osteocalcin secretion in a dose-dependent manner when the clone was maintained at 34 C (approximately 6-fold), and this stimulation was enhanced > 5 fold at 40 C. In contrast to the low expression of alkaline phosphatase, the cells secreted high amounts of osteocalcin in response to vitamin D3 (approximately 15 ng/mg cell protein); this biochemical profile also resembled that of preosteocytes. Cholecalciferol bone gamma-carboxyglutamate protein Homo sapiens
2 Vitamin D3 also increased osteocalcin secretion in a dose-dependent manner when the clone was maintained at 34 C (approximately 6-fold), and this stimulation was enhanced > 5 fold at 40 C. In contrast to the low expression of alkaline phosphatase, the cells secreted high amounts of osteocalcin in response to vitamin D3 (approximately 15 ng/mg cell protein); this biochemical profile also resembled that of preosteocytes. Cholecalciferol bone gamma-carboxyglutamate protein Homo sapiens