Title : Mutagenesis of thrombin selectively modulates inhibition by serpins heparin cofactor II and antithrombin III. Interaction with the anion-binding exosite determines heparin cofactor II specificity.

Pub. Date : 1993 Feb 15

PMID : 8429040






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Thrombin is inhibited by the serpins antithrombin III and heparin cofactor II in a reaction that is dramatically accelerated by glycosaminoglycans. Glycosaminoglycans serpin family C member 1 Homo sapiens