Title : Sulphydryl agents modulate insulin- and epidermal growth factor (EGF)-receptor kinase via reaction with intracellular receptor domains: differential effects on basal versus activated receptors.

Pub. Date : 1993 May 15

PMID : 8389126






1 Functional Relationships(s)
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1 These results contrast with those obtained with dithiothreitol which appears to activate phosphorylation in association with reduction of the extracellular insulin-receptor disulphides, but is without effect on the EGF receptor or the IRK protein. Dithiothreitol insulin receptor Homo sapiens