Title : Oxysterol-induced cell death in human leukemic T-cells correlates with oxysterol binding protein occupancy and is independent of glucocorticoid-induced apoptosis.

Pub. Date : 1993 Oct

PMID : 8217873






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 All cells studied herein possessed an oxysterol binding protein with high affinity for 25-hydroxycholesterol. 25-hydroxycholesterol oxysterol binding protein Homo sapiens
2 For all clones grown in serum-free medium, the half-maximal cytolytic concentration of 25-hydroxycholesterol (20-40 nM) correlated with its affinity (Kd = approximately 31 nM) for this oxysterol binding protein. 25-hydroxycholesterol oxysterol binding protein Homo sapiens