Title : Structural determinants of the action against Escherichia coli of a human inflammatory fluid phospholipase A2 in concert with polymorphonuclear leukocytes.

Pub. Date : 1994 Oct 21

PMID : 7929350

1 Functional Relationships(s)
Compound Name
Protein Name
1 We have examined by site-specific mutagenesis of a recombinant PLA2 that is identical to an enzyme in human synovial fluid (containing His-6, Arg-7, Lys-10, and Lys-15 and a global net charge of +15) the role of basic residues in this region in PLA2 action against PLA-deficient (pldA-) E. coli. Histidine phospholipase A2 group IB Homo sapiens