Title : Protein kinase C regulates MARCKS cycling between the plasma membrane and lysosomes in fibroblasts.

Pub. Date : 1995 Mar 15

PMID : 7720702






2 Functional Relationships(s)
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1 MARCKS phosphorylation is required for its translocation to lysosomes since mutating either the serine residues phosphorylated by PKC (phos-) or the PKC inhibitor staurosporine, prevented MARCKS phosphorylation, its release from the plasma membrane, and its subsequent association with lysosomes. Serine myristoylated alanine rich protein kinase C substrate Homo sapiens
2 MARCKS phosphorylation is required for its translocation to lysosomes since mutating either the serine residues phosphorylated by PKC (phos-) or the PKC inhibitor staurosporine, prevented MARCKS phosphorylation, its release from the plasma membrane, and its subsequent association with lysosomes. Serine myristoylated alanine rich protein kinase C substrate Homo sapiens