Title : Brefeldin A renders Chinese hamster ovary cells insensitive to transcriptional suppression by 25-hydroxycholesterol.

Pub. Date : 1995 Apr 7

PMID : 7713903






2 Functional Relationships(s)
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1 In the presence of BFA (1 microgram/ml), 25-hydroxycholesterol-mediated suppression of mRNAs for HMG-CoA reductase, the low density lipoprotein receptor, and farnesyl-diphosphate synthase was almost completely blocked. 25-hydroxycholesterol 3-hydroxy-3-methylglutaryl-coenzyme A reductase Cricetulus griseus
2 Monensin was also found to block the effects of 25-hydroxycholesterol on suppression of HMG-CoA reductase. 25-hydroxycholesterol 3-hydroxy-3-methylglutaryl-coenzyme A reductase Cricetulus griseus