Title : Vasopressin resistance in chronic renal failure. Evidence for the role of decreased V2 receptor mRNA.

Pub. Date : 1995 Jul

PMID : 7615808






1 Functional Relationships(s)
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1 CRF cells do respond normally to forskolin or cholera toxin and the defect in AVP responsiveness is not prevented by treatment with pertussis toxin, by cyclooxygenase inhibition, or by inhibition or down-regulation of protein kinase C. In contrast to their lack of responsiveness to AVP, CRF cells respond normally to other agonists of adenylyl cyclase such as isoproterenol or prostaglandin E2. Dinoprostone arginine vasopressin Rattus norvegicus