Title : Diabetes mellitus following pentamidine-induced hypoglycemia in humans.

Pub. Date : 1982 Jan

PMID : 6759211






2 Functional Relationships(s)
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Protein Name
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1 In vitro incubation of islets with pentamidine 10(-10) M produced a passive release of insulin, followed by a significant decrease in B-cell response to glucose + theophylline. Pentamidine insulin Homo sapiens
2 It is suggested that pentamidine can induce hypoglycemia because of an early cytolytic release of insulin, and then diabetes mellitus because of B-cell destruction and insulin deficiency. Pentamidine insulin Homo sapiens