Title : Activation of heparin cofactor II by dermatan sulfate.

Pub. Date : 1983 Jun 10

PMID : 6687888






2 Functional Relationships(s)
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1 The second order rate constant for the thrombin-HCII reaction reached a maximum value of 6.4 X 10(8) M-1 min-1 in the presence of 250-500 micrograms/ml of dermatan sulfate compared to 3.8 X 10(8) M-1 min-1 in the presence of 40-80 micrograms/ml of heparin. Dermatan Sulfate CD59 molecule (CD59 blood group) Homo sapiens
2 The second order rate constant for the thrombin-HCII reaction reached a maximum value of 6.4 X 10(8) M-1 min-1 in the presence of 250-500 micrograms/ml of dermatan sulfate compared to 3.8 X 10(8) M-1 min-1 in the presence of 40-80 micrograms/ml of heparin. Dermatan Sulfate CD59 molecule (CD59 blood group) Homo sapiens