Title : Circadian secretion of ACTH, cortisol, and mineralocorticoids in Cushing's syndrome.

Pub. Date : 1982

PMID : 6291816

2 Functional Relationships(s)
Compound Name
Protein Name
1 Few peaks of ACTH and cortisol were simultaneous and rare secretory impulses of corticosterone, and deoxycorticosterone were in synchrony with those of ACTH or cortisol. Desoxycorticosterone proopiomelanocortin Homo sapiens
2 appear to be essential in order to distinguish pituitary-dependent Cushing"s syndrome from normal; 2) In conditions of ACTH excess, DOC and corticosterone secretion seems to become progressively less ACTH-dependent as we proceed down the biosynthetic chain towards aldosterone, which is suppressed in most cases. Desoxycorticosterone proopiomelanocortin Homo sapiens