Title : Effects of bromocriptine and cyproheptadine on basal and corticotropin-releasing factor (CRF)-induced ACTH release in a patient with Nelson's syndrome.

Pub. Date : 1984 Oct

PMID : 6097444






4 Functional Relationships(s)
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1 Effects of bromocriptine and cyproheptadine on basal and corticotropin-releasing factor (CRF)-induced ACTH release in a patient with Nelson"s syndrome. Bromocriptine proopiomelanocortin Homo sapiens
2 Oral administration of either bromocriptine (2.5 mg) or cyproheptadine (8 mg) caused a marked drop in plasma ACTH levels. Bromocriptine proopiomelanocortin Homo sapiens
3 Short-term (3-week) treatment with either bromocriptine (7.5 mg/day) or cyproheptadine (12 mg/day) resulted in a marked suppression of basal ACTH release. Bromocriptine proopiomelanocortin Homo sapiens
4 It is suggested that bromocriptine and cyproheptadine are effective drugs in reducing basal and CRF-stimulated ACTH release, possibly acting at the pituitary level in this case. Bromocriptine proopiomelanocortin Homo sapiens