Title : A trifluoromethylphenyl piperazine derivative with high affinity for 5-hydroxytryptamine-1A sites in rat brain.

Pub. Date : 1985 Mar

PMID : 3838340






2 Functional Relationships(s)
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1 Spiperone inhibition of [3H]5-HT binding in cortex was consistent with displacement from two sites with dissociation constants (KD) of 24 nM (5-HT-1A site) and 19 microM (5-HT-1B site) for spiperone. Spiperone 5-hydroxytryptamine receptor 1B Rattus norvegicus
2 Spiperone inhibition of [3H]5-HT binding in cortex was consistent with displacement from two sites with dissociation constants (KD) of 24 nM (5-HT-1A site) and 19 microM (5-HT-1B site) for spiperone. Spiperone 5-hydroxytryptamine receptor 1B Rattus norvegicus