Title : Modified activity of Aeromonas aminopeptidase: metal ion substitutions and role of substrates.

Pub. Date : 1986 Dec 2

PMID : 3801458






1 Functional Relationships(s)
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1 The effects of metal ion substitutions on the susceptibility of the p-nitroanilides of L-alanine, L-valine, and L-leucine--substrates that are hydrolyzed at widely differing rates by native Aeromonas aminopeptidase--were studied by determining values of kcat and Km for the 16 metalloenzymes that result from all possible combinations of Zn2+, Co2+, Ni2+, and Cu2+ in each of the two sites. Alanine carboxypeptidase Q Homo sapiens