Title : Evidence That β1-Integrin Is Required for the Anti-Viability and Anti-Proliferative Effect of Resveratrol in CRC Cells.

Pub. Date : 2022 Apr 25

PMID : 35563105






1 Functional Relationships(s)
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1 Similarly, resveratrol-blocked TME-induced p65-NF-kB and its promoted gene markers linked to proliferation (cyclin D1), invasion (focal adhesion kinase, FAK), or apoptosis (caspase-3), were largely abrogated by anti-beta1-integrin or RGD peptide, suggesting that beta1-integrin is a potential transmission pathway for resveratrol/integrin down-stream signaling in CRC cells. Resveratrol caspase 3 Homo sapiens