Title : Disruption of peroxisome proliferator-activated receptor α in hepatocytes protects against acetaminophen-induced liver injury by activating the IL-6/STAT3 pathway.

Pub. Date : 2022

PMID : 35414769






1 Functional Relationships(s)
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1 ROS production rather than the expression levels of phase I and II cytochrome P450 enzymes was reduced in hepatocyte-specific Ppara knockout mice compared to control mice after acetaminophen administration. Reactive Oxygen Species peroxisome proliferator activated receptor alpha Mus musculus