Title : Network meta-analysis on efficacy and safety of different Janus kinase inhibitors for ulcerative colitis.

Pub. Date : 2022 Mar 6

PMID : 35253941






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Filgotinib 100 mg was ranked highest for induction of endoscopic remission (SUCRA, 0.67) whereas peficitinib 75 mg BID was ranked highest for induction of clinical response (SUCRA, 0.72). peficitinib BH3 interacting domain death agonist Homo sapiens
2 WHAT IS NEW AND CONCLUSION: Based on indirect comparisons, peficitinib 75 mg/75 mg BID/150 mg, tofacitinib 3 mg and filgotinib 100mg were the most efficacious JAK inhibitor interventions in patients with UC. peficitinib BH3 interacting domain death agonist Homo sapiens