Title : Demonstration that the insulin receptor undergoes an early structural modification following insulin binding.

Pub. Date : 1986 Apr 14

PMID : 3513838






1 Functional Relationships(s)
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1 Processing of the insulin receptor by hepatocytes was studied using a 125I-labelled photoreactive insulin derivative which could be covalently attached to the receptor and facilitate the analysis of receptor structure in isolated subcellular fractions by SDS-polyacrylamide gel electrophoresis. Sodium Dodecyl Sulfate insulin receptor Homo sapiens