Pub. Date : 2021
PMID : 35126177
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | MpkCCD cells expressed mRNAs for the receptors of PGE2 (EP1/EP4), PGF2 (FP), and TxB2 (TP). | Dinoprostone | prostaglandin E receptor 1 (subtype EP1) | Mus musculus |
| 2 | Moreover, in the presence of dDAVP, an EP1/3, but not EP4, agonist decreased the AQP2 abundance, and the addition of EP1 antagonists prevented the PGE2-mediated downregulation of AQP2. | Dinoprostone | prostaglandin E receptor 1 (subtype EP1) | Mus musculus |
| 3 | Our study shows that in mpkCCDc14 cells, reduced EP4 receptor and increased EP1/FP receptor expression by dDAVP explains the differential effects of PGE2 and PGF2alpha on AQP2 abundance with or without dDAVP. | Dinoprostone | prostaglandin E receptor 1 (subtype EP1) | Mus musculus |