Title : Nitazoxanide and Cancer Drug Resistance: Targeting Wnt/β-catenin Signaling Pathway.

Pub. Date : 2022 Apr

PMID : 34937659






1 Functional Relationships(s)
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1 Furthermore, NTZ downregulated Wnt/beta-catenin signaling pathway through significant decrease of CTNNB1, c-Myc, ABCB1, and cyclin D1 genes and resulted in drug resistance reversal and inhibition of cell proliferation. nitazoxanide MYC proto-oncogene, bHLH transcription factor Homo sapiens