Title : The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer.

Pub. Date : 2021 Dec 16

PMID : 34919819






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Binding of PARP1 to damaged DNA leads to activation wherein PARP1 uses NAD+ to add chains of poly(ADP-ribose) onto itself and other nuclear proteins. NAD poly(ADP-ribose) polymerase 1 Homo sapiens
2 Binding of PARP1 to damaged DNA leads to activation wherein PARP1 uses NAD+ to add chains of poly(ADP-ribose) onto itself and other nuclear proteins. NAD poly(ADP-ribose) polymerase 1 Homo sapiens